![]() ![]() In the most common setting of cyanide inhalation with residential fires and no rapid cyanide diagnostic test, administration without true cyanide exposure would inadvertently harm the victim. Inject sodium thiosulfate IV 7 g/sq.meter over 10 minutes not to exceed 12. This could be related to the prior cyanide antidote kit containing sodium nitrate and amyl nitrite which both can cause methemoglobinemia. Many clinicians will administer only sodium thiosulfate portion if concerned of concomitant carboxyhemoglobinemia, or if ingestion is uncertainĪdminister amyl nitrite as in adults crush 0.3 mL ampul of amyl nitrite q1min and inhale vapor for 15-30 seconds until IV sodium nitrite infusion availableįollow amyl nitrite administration with sodium nitrate 10 mg/kg (0.33 mL/kg or 6-8 mL/sq.meter of 3% solution not to exceed 10 mL) ![]() Vasopressors should be available to treat shockĬurrently manufactured by Akorn, Inc, Buffalo Grove, IL (1-80) amyl nitrite inhalant: 0.3mL (12 ampules)Ĭrush 0.3 mL ampul of amyl nitrite q1min and inhale vapor for 15-30 seconds until IV sodium nitrite infusion availableįollowing infusion of 300 mg or 10 mg/kg IV sodium nitrate, over 2-5 minutes, inject 12.5 g sodium thiosulfate IV over 10 minutes PRN may repeat both injections at 1/2 original dose. ![]() sodium thiosulfate injection: 12.5g/50mL (2 vials) sodium nitrite: 300mg/10mL (2 ampules) amyl nitrite inhalant: 0. Cyanide Poisoning (Off-label) 0. Discontinued from United States market May 2012.
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